High-Value Targeting is a risk-based vulnerability management capability within the Horizon3.ai NodeZero platform. The product focuses on identifying and prioritizing security risks based on the value of potential targets within an organization's environment. The solution operates as part of NodeZero's autonomous penetration testing platform, which performs internal, external, cloud, and Kubernetes security assessments. High-Value Targeting helps organizations understand which assets are most critical and vulnerable to attack by simulating real-world threat actor behavior. The platform uses autonomous testing to identify attack paths that could lead to compromise of high-value assets. It provides threat-informed perspectives by incorporating threat actor intelligence and vulnerability risk intelligence to prioritize remediation efforts based on actual exploitability and business impact. High-Value Targeting integrates with NodeZero's broader security validation capabilities, including endpoint security effectiveness testing, identity security validation, and Active Directory security assessments. The platform generates actionable reports that help security teams understand which vulnerabilities pose the greatest risk to their most valuable assets. The solution supports compliance requirements including PCI and NIS 2, and can be deployed across hybrid environments including on-premises infrastructure, cloud platforms, and containerized workloads. Organizations can use High-Value Targeting to validate security controls, test threat detection and response capabilities, and assess third-party risk.