Microsoft Defender for Endpoint vs Prelude Security RMP: Side-by-Side Comparison (2026)

Microsoft Defender for Endpoint: Multiplatform endpoint security with detection and response capabilities. built by Microsoft. Core capabilities include Endpoint detection and response (EDR), Automatic attack disruption for ransomware, Exposure management..

Prelude Security RMP: Endpoint agent detecting in-memory malicious code execution on Windows. built by Prelude Security. Core capabilities include Detection of malicious in-memory code execution, Hardware-focused telemetry collection, Asynchronous processing at the edge..

Both serve the Endpoint Detection and Response market but differ in approach, feature depth, and target audience.

Microsoft Defender for Endpoint differentiates with Endpoint detection and response (EDR), Automatic attack disruption for ransomware, Exposure management. Prelude Security RMP differentiates with Detection of malicious in-memory code execution, Hardware-focused telemetry collection, Asynchronous processing at the edge.

Microsoft Defender for Endpoint is developed by Microsoft. Prelude Security RMP is developed by Prelude Security. Vendor maturity, funding stage, and team size can be important factors when evaluating long-term viability and support quality.

Microsoft Defender for Endpoint and Prelude Security RMP serve similar Endpoint Detection and Response use cases: both are Endpoint Detection and Response tools. Review the feature comparison above to determine which fits your requirements.