Cisco Duo Remote Access vs Zscaler Secure Private Access with ZTNA: Side-by-Side Comparison (2026)

Cisco Duo Remote Access: Remote access security solution with phishing-resistant MFA and device trust. built by Duo Security. Core capabilities include Phishing-resistant multi-factor authentication, Device trust verification, VPN-less remote access..

Zscaler Secure Private Access with ZTNA: ZTNA solution providing secure user-to-app access without network exposure. built by Zscaler. Core capabilities include AI-powered application segmentation with automated discovery and policy recommendations, User-to-app direct connections without network exposure, Workload-to-workload segmentation across hybrid and multicloud environments..

Both serve the Zero Trust Network Access market but differ in approach, feature depth, and target audience.

Cisco Duo Remote Access differentiates with Phishing-resistant multi-factor authentication, Device trust verification, VPN-less remote access. Zscaler Secure Private Access with ZTNA differentiates with AI-powered application segmentation with automated discovery and policy recommendations, User-to-app direct connections without network exposure, Workload-to-workload segmentation across hybrid and multicloud environments.

Cisco Duo Remote Access is developed by Duo Security. Zscaler Secure Private Access with ZTNA is developed by Zscaler. Vendor maturity, funding stage, and team size can be important factors when evaluating long-term viability and support quality.

Cisco Duo Remote Access and Zscaler Secure Private Access with ZTNA serve similar Zero Trust Network Access use cases: both are Zero Trust Network Access tools, both cover Remote Access, ZTNA. Review the feature comparison above to determine which fits your requirements.