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Agilicus is a commercial zero trust network access tool by Agilicus. Cyolo PRO is a commercial zero trust network access tool by Cyolo. Compare features, ratings, integrations, and community reviews side by side to find the best zero trust network access fit for your security stack.
Based on our analysis of NIST CSF 2.0 coverage, core features, integrations, company size fit, here is our conclusion:
Teams protecting OT and ICS environments without the luxury of deploying agents will find Agilicus solves a real problem: clientless zero trust access to PLCs, HMIs, and SCADA systems that can't run traditional security software. The no-inbound-ports architecture means your critical infrastructure never exposes attack surface to the internet, and support for federated identity providers lets you enforce MFA across resources that typically have none. Skip this if your primary concern is securing standard IT applications and desktops; plenty of lighter-weight ZTNA platforms handle that use case better and cheaper.
Mid-market and enterprise teams managing OT/ICS environments or air-gapped networks should consider Cyolo PRO because it handles legacy system authentication without rip-and-replace, which most zero-trust vendors skip entirely. The tool covers NIST PR.AA (identity and access control) and DE.CM (continuous monitoring) with session visibility baked in, and it deploys hybrid across disconnected infrastructure where cloud-native alternatives fail. Skip this if your priority is identity governance and entitlement management; Cyolo focuses on access enforcement, not the upstream IAM workflow.
Clientless ZTNA platform for secure access to apps, OT, and ICS resources.
Secure remote access solution for OT/ICS environments with zero-trust access
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Common questions about comparing Agilicus vs Cyolo PRO for your zero trust network access needs.
Agilicus: Clientless ZTNA platform for secure access to apps, OT, and ICS resources. built by Agilicus. headquartered in Canada. Core capabilities include Clientless, agentless secure access to applications, desktops, shares, and OT resources, Multi-factor authentication (MFA) enforcement across all resource types, Single sign-on (SSO) via federated identity providers..
Cyolo PRO: Secure remote access solution for OT/ICS environments with zero-trust access. built by Cyolo. headquartered in Israel. Core capabilities include Identity-based authentication with multi-factor authentication, Zero-trust network connectivity, Credential vaulting and password rotation..
Both serve the Zero Trust Network Access market but differ in approach, feature depth, and target audience.
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