Zscaler AI Runtime Protection vs Zscaler SPLX AI Runtime Threat Inspection: Side-by-Side Comparison (2026)

Short answer

Mid-market and enterprise teams deploying LLMs at scale need Zscaler AI Runtime Protection primarily for its near-zero latency filtering of prompt injections and jailbreaks without slowing inference. The tool's real-time detection paired with full prompt and response logging addresses NIST DE.CM and DE.AE requirements that most AI security offerings skip over. Skip this if your organization runs fewer than three LLM applications in production or needs post-incident recovery capabilities; Zscaler is detection and blocking only, not forensic reconstruction. Security teams deploying internal GenAI applications need visibility into LLM interactions for prompt injection, data exfiltration, and jailbreak attempts,exactly what Zscaler SPLX AI Runtime Threat Inspection does through near real-time log analysis with 25+ AI-specific threat detectors. The low false positive rate and automated risk triage mean your team spends time on actual incidents, not tuning alerts. Skip this if you're looking for broader AI governance or model supply chain security; SPLX owns the runtime detection layer only.