Romana vs Illumio Segmentation: 2026 Comparison

Illumio Segmentation

Enterprise and mid-market security teams with hybrid multi-cloud footprints should pick Illumio Segmentation if lateral movement containment is your primary concern; the platform maps application dependencies in real time and enforces least-privilege policies across data centers, containers, and cloud workloads simultaneously. Its strength in continuous monitoring and incident mitigation (NIST DE.CM and RS.MI) means you get fast breach containment, though the tool prioritizes preventing spread over detecting the initial compromise. Skip this if your environment is cloud-native only or if you need EDR-level endpoint visibility; Illumio assumes you already have detection tooling in place.