Armis Centrix™ vs Zscaler Secure Private Access with ZTNA: Side-by-Side Comparison (2026)

Short answer

Mid-market and enterprise security teams managing sprawling IoT, OT, and medical device environments will get the most from Armis Centrix™ because its agentless discovery actually works across protocols most tools ignore. The platform covers all four NIST Identify and Detect functions, with particular strength in continuous asset monitoring and vulnerability prioritization that cuts through noise in environments with thousands of unmanaged devices. Not the pick if you need deep forensic analysis or incident response automation; Centrix prioritizes visibility and risk ranking over post-breach investigation. Mid-market and enterprise security teams replacing VPN with zero trust will find Zscaler Secure Private Access with ZTNA most valuable for its application segmentation that actually works without network discovery hell; the AI-powered policy automation cuts weeks of manual access mapping. The workload-to-workload segmentation across hybrid and multicloud environments maps directly to NIST PR.AA identity controls, and the inline Layer 7 inspection prevents the access-granted-now-exploited-later scenario that plagues simpler ZTNA deployments. Skip this if you need the strictest on-premises-only architecture or lack the hybrid infrastructure to justify the complexity; pure network microsegmentation tools will do less and cost less.