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Agilicus is a commercial zero trust network access tool by Agilicus. Illumio Policy Compute Engine is a commercial zero trust network access tool by Illumio. Compare features, ratings, integrations, and community reviews side by side to find the best zero trust network access fit for your security stack.
CST VerdictBased on our analysis of NIST CSF 2.0 coverage, core features, integrations, company size fit, here is our conclusion:
Teams protecting OT and ICS environments without the luxury of deploying agents will find Agilicus solves a real problem: clientless zero trust access to PLCs, HMIs, and SCADA systems that can't run traditional security software. The no-inbound-ports architecture means your critical infrastructure never exposes attack surface to the internet, and support for federated identity providers lets you enforce MFA across resources that typically have none. Skip this if your primary concern is securing standard IT applications and desktops; plenty of lighter-weight ZTNA platforms handle that use case better and cheaper.
Enterprise and mid-market security teams managing sprawling hybrid infrastructure should buy Illumio Policy Compute Engine for its ability to enforce least-privilege access at scale without requiring network redesign. The platform ingests real-time telemetry across cloud and on-premises environments and converts application dependencies into executable policy, reducing the manual labor that kills most microsegmentation projects; NIST PR.IR coverage reflects that infrastructure-first design. Skip this if your organization lacks mature application inventory or isn't ready to commit to dependency mapping as foundational work; Illumio excels at containment and policy automation, not at discovery shortcuts.
Clientless ZTNA platform for secure access to apps, OT, and ICS resources.
Centralized policy engine for microsegmentation and breach containment
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Common questions about comparing Agilicus vs Illumio Policy Compute Engine for your zero trust network access needs.
Agilicus: Clientless ZTNA platform for secure access to apps, OT, and ICS resources. built by Agilicus. headquartered in Canada. Core capabilities include Clientless, agentless secure access to applications, desktops, shares, and OT resources, Multi-factor authentication (MFA) enforcement across all resource types, Single sign-on (SSO) via federated identity providers..
Illumio Policy Compute Engine: Centralized policy engine for microsegmentation and breach containment. built by Illumio. headquartered in United States. Core capabilities include Application dependency mapping, Policy simulation and modeling, Context-aware policy computation using metadata..
Both serve the Zero Trust Network Access market but differ in approach, feature depth, and target audience.
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