1stProtect.ai vs ThreatLocker Detect: Side-by-Side Comparison (2026)

1stProtect.ai: Runtime enforcement platform with 22 modules on one SIGMA engine, offline-capable. built by 1stProtect.ai. Core capabilities include Single user-space SIGMA engine replacing multiple legacy security engines (EPP, EDR, DLP, IAM, ITDR, SASE), 22 protection modules covering credential theft, ransomware, data exfiltration, process injection, browser attacks, and agent self-defense, Offline-first policy enforcement with local policy engine cached in kernel memory — no cloud dependency required..

ThreatLocker Detect: Policy-based EDR solution monitoring endpoints for IoCs with automated responses. built by threatlocker. Core capabilities include Policy-based detection and response rules, Real-time monitoring of endpoint behavior, Automated responses including lockdown mode..

Both serve the Endpoint Detection and Response market but differ in approach, feature depth, and target audience.

1stProtect.ai differentiates with Single user-space SIGMA engine replacing multiple legacy security engines (EPP, EDR, DLP, IAM, ITDR, SASE), 22 protection modules covering credential theft, ransomware, data exfiltration, process injection, browser attacks, and agent self-defense, Offline-first policy enforcement with local policy engine cached in kernel memory — no cloud dependency required. ThreatLocker Detect differentiates with Policy-based detection and response rules, Real-time monitoring of endpoint behavior, Automated responses including lockdown mode.

1stProtect.ai is developed by 1stProtect.ai. ThreatLocker Detect is developed by threatlocker. Vendor maturity, funding stage, and team size can be important factors when evaluating long-term viability and support quality.

1stProtect.ai and ThreatLocker Detect serve similar Endpoint Detection and Response use cases: both are Endpoint Detection and Response tools. Review the feature comparison above to determine which fits your requirements.