Microsoft Defender for Office 365 vs ThreatDown Email Security: side-by-side comparison (2026)

Microsoft Defender for Office 365: Email and collaboration security for Microsoft 365 environments. Built by Microsoft.

ThreatDown Email Security: AI-powered email security platform for phishing and BEC protection. Built by ThreatDown by Malwarebytes.

The table above shows where their features, integrations, deployment and company size fit differ.

Microsoft Defender for Office 365 is made by Microsoft. ThreatDown Email Security is made by ThreatDown by Malwarebytes. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

Often, yes. Microsoft Defender for Office 365 and ThreatDown Email Security are both Email Security Platforms products. Use the table above to see where features, deployment and company size fit differ.