Sophos EDR vs Uptycs Nexus: side-by-side comparison (2026)
Sophos EDR is a commercial endpoint detection and response solution by Sophos. Uptycs Nexus is a commercial endpoint detection and response solution by Uptycs. Features, integrations, deployment and the company behind each one, side by side.
Our take
What our shortlists say about the one we picked.
- Sophos EDR
Best for: Teams already running Sophos Endpoint
It belongs here for teams that already run Sophos Endpoint, because EDR turns on from the same console without a new agent. It fits teams of any size that want AI help ranking and summing up detections. You can also run it with Microsoft Defender as the protection agent, which helps if you are moving between the two.
From Best EDR Solutions for Business, Fall 2026
Reviewed by Nika (Nikoloz) Kokhreidze.
KnocknocSponsored
Hi Citrix. Hide VPNs. Hide Windows on a LAN. Knocknoc solves this. Just in time identity linked allow-listing. DIY, on-premise or SaaS. Prevent attacks fast.
VisitEndpoint detection and response that finds and stops human-led attacks.
Managed SaaS for osquery fleet management across endpoints
Side-by-side comparison
Feature
Sophos EDR
Uptycs Nexus
Pricing model
Commercial
Commercial
Category
Endpoint Detection and Response
Endpoint Detection and Response
Deployment and fit
Deployment type
Hybrid
Cloud
Company size fit
SMB, Mid-Market, Enterprise
Startup, SMB, Mid-Market, Enterprise
Company
Company
Sophos
Uptycs
Use cases and capabilities
Ransomware Prevention
Yes
No
osquery
No
Yes
Core features
10 features listed
10 features listed
Integrations
1 integration listed
6 integrations listed
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