Microsoft Defender for Endpoint is a commercial endpoint detection and response solution by Microsoft. OpenEDR is a free endpoint detection and response solution. Features, integrations, deployment and the company behind each one, side by side.
What our shortlists say about the one we picked.
Best for: Teams already running Microsoft 365
It earns a place because it covers phones as well as desktops and servers, and many companies already own it through their Microsoft 365 license, so the first question is what you have paid for already. Its alerts flow into Microsoft's other security products, which suits a Microsoft-centric estate of any size. If you run a mixed stack, test how well its alerts reach the SIEM and SOAR you already use.
From Best Endpoint Security Solutions for Business, Fall 2026
Reviewed by Nika (Nikoloz) Kokhreidze.
Hi Citrix. Hide VPNs. Hide Windows on a LAN. Knocknoc solves this. Just in time identity linked allow-listing. DIY, on-premise or SaaS. Prevent attacks fast.
VisitMultiplatform endpoint security with detection and response capabilities
OpenEDR is an open-source platform enhancing cybersecurity through real-time detection and analysis of cyber threats.
See more solutions in this category, or build a security stack from your picks.
Need the answer fast? Best EDR Solutions for Business picks CrowdStrike Agentic Endpoint Security, Microsoft Defender for Endpoint, SentinelOne Singularity Endpoint and 4 more.See the shortlist
Based on what each listing shows: deployment, company size, price and open source.
Microsoft Defender for Endpoint fits if you want a cloud product.
OpenEDR fits if you need to run it on your own servers, you are a startup and you need a free product.
Common questions when comparing Microsoft Defender for Endpoint vs OpenEDR for endpoint detection and response.
Microsoft Defender for Endpoint: Multiplatform endpoint security with detection and response capabilities, built by Microsoft.
OpenEDR: OpenEDR is an open-source platform enhancing cybersecurity through real-time detection and analysis of cyber threats.
The table above shows where their features, integrations, deployment and company size fit differ.
Often, yes. Microsoft Defender for Endpoint and OpenEDR are both Endpoint Detection and Response products. Key differences: Microsoft Defender for Endpoint is Commercial while OpenEDR is Free. Use the table above to see where features, deployment and company size fit differ.