- Microsoft Defender for Endpoint
Best for: Teams already running Microsoft 365
It earns a place because it covers phones as well as desktops and servers, and many companies already own it through their Microsoft 365 license, so the first question is what you have paid for already. Its alerts flow into Microsoft's other security products, which suits a Microsoft-centric estate of any size. If you run a mixed stack, test how well its alerts reach the SIEM and SOAR you already use.
From Best Endpoint Security Solutions for Business, Fall 2026
- Tanium Threat Response
Best for: Teams hunting across very large endpoint fleets
It is on this list for hunting and response across very large fleets, because it can question every endpoint in real time, online or offline. It often runs next to another EDR, which suits teams that want deeper hunting on top of what they have. If you do not already use Tanium for inventory or patching, weigh the cost of a new agent for this one job.
From Best EDR Solutions for Business, Fall 2026
