Palo Alto Networks Prisma Access ZTNA 2.0 vs ThreatLocker Zero Trust Network Access: side-by-side comparison (2026)

Palo Alto Networks Prisma Access ZTNA 2.0: Cloud-delivered ZTNA 2.0 for private apps with app-level least-privilege access, built by Palo Alto Networks.

ThreatLocker Zero Trust Network Access: ZTNA that brokers access from authorized users/devices to internal resources, no VPN, built by ThreatLocker.

The table above shows where their features, integrations, deployment and company size fit differ.

Palo Alto Networks Prisma Access ZTNA 2.0 is made by Palo Alto Networks. ThreatLocker Zero Trust Network Access is made by ThreatLocker. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

Often, yes. Palo Alto Networks Prisma Access ZTNA 2.0 and ThreatLocker Zero Trust Network Access are both Zero Trust Network Access products, and both cover ZTNA, Remote Access, Least Privilege. Use the table above to see where features, deployment and company size fit differ.