Netskope One is a commercial secure access service edge solution by Netskope. Palo Alto Networks Prisma Access is a commercial secure access service edge solution by Palo Alto Networks. Features, integrations, deployment and the company behind each one, side by side.
What our shortlists say about the one we picked.
Best for: Enterprises that want the full security stack on a hyperscale backbone
It fits SMB through enterprise in our data, but the economics and the operational model favor organizations that already run Palo Alto or have the team to adopt its policy framework. Pricing is not published.
From Best SASE Solutions for Business, Fall 2026
Reviewed by Nika (Nikoloz) Kokhreidze.
Cloud-native SASE platform with converged security and networking services
Cloud-delivered SASE solution securing users, apps, devices, and data everywhere
See more solutions in this category, or build a security stack from your picks.
Common questions when comparing Netskope One vs Palo Alto Networks Prisma Access for secure access service edge.
Netskope One: Cloud-native SASE platform with converged security and networking services. Built by Netskope.
Palo Alto Networks Prisma Access: Cloud-delivered SASE solution securing users, apps, devices, and data everywhere. Built by Palo Alto Networks.
The table above shows where their features, integrations, deployment and company size fit differ.
Netskope One is made by Netskope. Palo Alto Networks Prisma Access is made by Palo Alto Networks. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.
Often, yes. Netskope One and Palo Alto Networks Prisma Access are both Secure Access Service Edge products, and both cover SASE, SD-WAN, ZTNA. Use the table above to see where features, deployment and company size fit differ.
Need the answer fast? Best SASE Solutions for Business picks Cato Networks Cato SASE, Palo Alto Networks Prisma SASE, Zscaler Zero Trust Exchange Platform and 4 more.See the shortlist
