Microsoft Defender XDR is a commercial extended detection and response solution by Microsoft. SentinelOne is a commercial extended detection and response solution by SentinelOne. Features, integrations, deployment and the company behind each one, side by side.
XDR solution for unified detection and response across Microsoft 365
AI-driven endpoint protection platform for threat detection and response
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Common questions when comparing Microsoft Defender XDR vs SentinelOne for extended detection and response.
Microsoft Defender XDR: XDR solution for unified detection and response across Microsoft 365. Built by Microsoft.
SentinelOne: AI-driven endpoint protection platform for threat detection and response. Built by SentinelOne.
The table above shows where their features, integrations, deployment and company size fit differ.
Microsoft Defender XDR is made by Microsoft. SentinelOne is made by SentinelOne. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.
Often, yes. Microsoft Defender XDR and SentinelOne are both Extended Detection and Response products. Use the table above to see where features, deployment and company size fit differ.
No Extended Detection and Response shortlist yet. This is the closest one.
Updated 2026-11-02
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