# Palo Alto Networks Medical Device Security vs Portnox CORE: side-by-side comparison (2026)

[Palo Alto Networks Medical Device Security](https://cybersectools.com/tools/palo-alto-networks-medical-device-security) is a commercial [medical device security](https://cybersectools.com/categories/medical-device-security) solution by [Palo Alto Networks](https://cybersectools.com/companies/palo-alto-networks). [Portnox CORE](https://cybersectools.com/tools/portnox-core) is a commercial [network access control](https://cybersectools.com/categories/nac) solution by [Portnox](https://cybersectools.com/companies/portnox). Features, integrations, deployment and the company behind each one, side by side.

## Our take

What our shortlists say about the one we picked.

### [Palo Alto Networks Medical Device Security](https://cybersectools.com/tools/palo-alto-networks-medical-device-security)

Best for: Hospitals that need device visibility and policy enforcement on the Palo Alto network

It fits mid-market and enterprise and is hybrid-deployable. The case is strongest for healthcare organizations already running Palo Alto Networks firewalls, where the policy enforcement is native.

From [Best OT Security Solutions for Business](https://cybersectools.com/shortlists/best-ot-security-solutions), Fall 2026.

Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about).

## Side-by-side comparison

| | Palo Alto Networks Medical Device Security | Portnox CORE |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Medical Device Security | Network Access Control |
| Verified | No | No |
| Deployment type | Hybrid | On-Premises |
| Company size fit | Mid-Market, Enterprise | SMB, Mid-Market, Enterprise |
| Company | Palo Alto Networks | Portnox |
| Headquarters | – | – |

### Use cases and capabilities

| | Palo Alto Networks Medical Device Security | Portnox CORE |
|---|---|---|
| Healthcare | Yes | – |
| IoT Security | Yes | Yes |
| Network Visibility | – | Yes |
| BYOD | – | Yes |

### Core features

**Palo Alto Networks Medical Device Security**

8 features listed. Sign in on the page to see them.

**Portnox CORE**

10 features listed. Sign in on the page to see them.

### Integrations

**Palo Alto Networks Medical Device Security**

2 integrations listed. Sign in on the page to see them.

**Portnox CORE**

6 integrations listed. Sign in on the page to see them.

## Which one fits you

Based on what each listing shows: deployment, company size, price and open source.

- [Palo Alto Networks Medical Device Security](https://cybersectools.com/tools/palo-alto-networks-medical-device-security) fits if you need both cloud and on-premises options.
- [Portnox CORE](https://cybersectools.com/tools/portnox-core) fits if you need to run it on your own servers and you are a small business.

## Palo Alto Networks Medical Device Security vs Portnox CORE FAQ

Common questions when comparing Palo Alto Networks Medical Device Security vs Portnox CORE for medical device security.

### What is the difference between Palo Alto Networks Medical Device Security and Portnox CORE?

**Palo Alto Networks Medical Device Security**: Secures medical devices with visibility, risk assessment, and policy enforcement, built by Palo Alto Networks.

**Portnox CORE**: On-premise NAC solution for device visibility and network access control, built by Portnox.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Palo Alto Networks Medical Device Security and Portnox CORE?

**Palo Alto Networks Medical Device Security** is made by Palo Alto Networks. **Portnox CORE** is made by Portnox. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Palo Alto Networks Medical Device Security a good alternative to Portnox CORE?

In part. Palo Alto Networks Medical Device Security and Portnox CORE are not in the same category on CybersecTools. Both cover IoT Security. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Palo Alto Networks Medical Device Security vs Axonius Unified Device Observability](https://cybersectools.com/compare/axonius-unified-device-observability-vs-palo-alto-networks-medical-device-security)
- [Palo Alto Networks Medical Device Security vs Armis Centrix™ for Medical Device Security](https://cybersectools.com/compare/armis-centrixtm-for-medical-device-security-vs-palo-alto-networks-medical-device-security)
- [Palo Alto Networks Medical Device Security vs Armis Centrix™ Medical Device Security](https://cybersectools.com/compare/armis-centrixtm-medical-device-security-vs-palo-alto-networks-medical-device-security)
- [Portnox CORE vs Axonius Unified Device Observability](https://cybersectools.com/compare/axonius-unified-device-observability-vs-portnox-core)
- [Portnox CORE vs Armis Centrix™ for Medical Device Security](https://cybersectools.com/compare/armis-centrixtm-for-medical-device-security-vs-portnox-core)
- [Portnox CORE vs Armis Centrix™ Medical Device Security](https://cybersectools.com/compare/armis-centrixtm-medical-device-security-vs-portnox-core)

## Alternatives to each

- [See all Palo Alto Networks Medical Device Security alternatives](https://cybersectools.com/alternatives/palo-alto-networks-medical-device-security)
- [See all Portnox CORE alternatives](https://cybersectools.com/alternatives/portnox-core)

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Source: https://cybersectools.com/compare/palo-alto-networks-medical-device-security-vs-portnox-core

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/palo-alto-networks-medical-device-security.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on Palo Alto Networks Medical Device Security and Portnox CORE: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md
