# Microsoft Defender XDR vs SentinelOne: side-by-side comparison (2026)

[Microsoft Defender XDR](https://cybersectools.com/tools/microsoft-defender-xdr) is a commercial [extended detection and response](https://cybersectools.com/categories/xdr) solution by [Microsoft](https://cybersectools.com/companies/microsoft). [SentinelOne](https://cybersectools.com/tools/sentinelone) is a commercial [extended detection and response](https://cybersectools.com/categories/xdr) solution by [SentinelOne](https://cybersectools.com/companies/sentinelone). Features, integrations, deployment and the company behind each one, side by side.

## Side-by-side comparison

| | Microsoft Defender XDR | SentinelOne |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Extended Detection and Response | Extended Detection and Response |
| Verified | No | No |
| Deployment type | Cloud | Cloud |
| Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise |
| Company | Microsoft | SentinelOne |
| Headquarters | – | – |

### Use cases and capabilities

| | Microsoft Defender XDR | SentinelOne |
|---|---|---|
| MITRE ATT&CK | Yes | – |

### Core features

**Microsoft Defender XDR**

10 features listed. Sign in on the page to see them.

**SentinelOne**

4 features listed. Sign in on the page to see them.

### Integrations

**Microsoft Defender XDR**

3 integrations listed. Sign in on the page to see them.

**SentinelOne**

No integrations listed.

## Microsoft Defender XDR vs SentinelOne FAQ

Common questions when comparing Microsoft Defender XDR vs SentinelOne for extended detection and response.

### What is the difference between Microsoft Defender XDR and SentinelOne?

**Microsoft Defender XDR**: XDR solution for unified detection and response across Microsoft 365. Built by Microsoft.

**SentinelOne**: AI-driven endpoint protection platform for threat detection and response. Built by SentinelOne.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Microsoft Defender XDR and SentinelOne?

**Microsoft Defender XDR** is made by Microsoft. **SentinelOne** is made by SentinelOne. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Microsoft Defender XDR a good alternative to SentinelOne?

Often, yes. Microsoft Defender XDR and SentinelOne are both Extended Detection and Response products. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Microsoft Defender XDR vs Cisco XDR](https://cybersectools.com/compare/cisco-xdr-vs-microsoft-defender-xdr)
- [Microsoft Defender XDR vs Seqrite XDR](https://cybersectools.com/compare/microsoft-defender-xdr-vs-seqrite-xdr)
- [Microsoft Defender XDR vs Palo Alto Networks Cortex XSIAM](https://cybersectools.com/compare/microsoft-defender-xdr-vs-palo-alto-networks-cortex-xsiam)
- [SentinelOne vs Cisco XDR](https://cybersectools.com/compare/cisco-xdr-vs-sentinelone)
- [SentinelOne vs Seqrite XDR](https://cybersectools.com/compare/sentinelone-vs-seqrite-xdr)
- [SentinelOne vs Palo Alto Networks Cortex XSIAM](https://cybersectools.com/compare/palo-alto-networks-cortex-xsiam-vs-sentinelone)

## Alternatives to each

- [See all Microsoft Defender XDR alternatives](https://cybersectools.com/alternatives/microsoft-defender-xdr)
- [See all SentinelOne alternatives](https://cybersectools.com/alternatives/sentinelone)

---

Source: https://cybersectools.com/compare/microsoft-defender-xdr-vs-sentinelone

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/microsoft-defender-xdr.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on Microsoft Defender XDR and SentinelOne: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md