# Microsoft Defender for Endpoint vs SentinelOne Singularity Endpoint: side-by-side comparison (2026) [Microsoft Defender for Endpoint](https://cybersectools.com/tools/microsoft-defender-for-endpoint) is a commercial [endpoint detection and response](https://cybersectools.com/categories/edr) solution by [Microsoft](https://cybersectools.com/companies/microsoft). [SentinelOne Singularity Endpoint](https://cybersectools.com/tools/sentinelone-singularity-endpoint) is a commercial [endpoint detection and response](https://cybersectools.com/categories/edr) solution by [SentinelOne](https://cybersectools.com/companies/sentinelone). Features, integrations, deployment and the company behind each one, side by side. ## Our take What our shortlists say about each one. ### [Microsoft Defender for Endpoint](https://cybersectools.com/tools/microsoft-defender-for-endpoint) Best for: Teams already running Microsoft 365 It earns a place because it covers phones as well as desktops and servers, and many companies already own it through their Microsoft 365 license, so the first question is what you have paid for already. Its alerts flow into Microsoft's other security products, which suits a Microsoft-centric estate of any size. If you run a mixed stack, test how well its alerts reach the SIEM and SOAR you already use. From [Best Endpoint Security Solutions for Business](https://cybersectools.com/shortlists/best-endpoint-security-solutions), Fall 2026. ### [SentinelOne Singularity Endpoint](https://cybersectools.com/tools/sentinelone-singularity-endpoint) Best for: Teams wanting automatic response and rollback Its place comes from response it can run on its own, with AI on the device that works offline and rollback in one click. It suits teams of any size that are short on analysts and want the agent to act first. It also covers identity attacks and mobile devices, so decide whether you want those in scope now or later. From [Best EDR Solutions for Business](https://cybersectools.com/shortlists/best-edr-solutions), Fall 2026. Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about). Need the answer fast? [Best EDR Solutions for Business](https://cybersectools.com/shortlists/best-edr-solutions) picks CrowdStrike Agentic Endpoint Security, Microsoft Defender for Endpoint, SentinelOne Singularity Endpoint and 4 more. ## Side-by-side comparison | | Microsoft Defender for Endpoint | SentinelOne Singularity Endpoint | |---|---|---| | Pricing model | Commercial | Commercial | | Category | Endpoint Detection and Response | Endpoint Detection and Response | | Verified | No | No | | Deployment type | Cloud | Cloud | | Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise | | Company | Microsoft | SentinelOne | | Headquarters | – | – | ### Use cases and capabilities | | Microsoft Defender for Endpoint | SentinelOne Singularity Endpoint | |---|---|---| | Ransomware Prevention | Yes | Yes | | Anomaly Detection | – | Yes | ### Core features **Microsoft Defender for Endpoint** 10 features listed. Sign in on the page to see them. **SentinelOne Singularity Endpoint** 10 features listed. Sign in on the page to see them. ### Integrations **Microsoft Defender for Endpoint** 29 integrations listed. Sign in on the page to see them. **SentinelOne Singularity Endpoint** 20 integrations listed. Sign in on the page to see them. ## Microsoft Defender for Endpoint vs SentinelOne Singularity Endpoint FAQ Common questions when comparing Microsoft Defender for Endpoint vs SentinelOne Singularity Endpoint for endpoint detection and response. ### What is the difference between Microsoft Defender for Endpoint and SentinelOne Singularity Endpoint? **Microsoft Defender for Endpoint**: Multiplatform endpoint security with detection and response capabilities, built by Microsoft. **SentinelOne Singularity Endpoint**: AI-powered endpoint protection platform with EDR and identity security, built by SentinelOne. The table above shows where their features, integrations, deployment and company size fit differ. ### Who makes Microsoft Defender for Endpoint and SentinelOne Singularity Endpoint? **Microsoft Defender for Endpoint** is made by Microsoft. **SentinelOne Singularity Endpoint** is made by SentinelOne. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit. ### Is Microsoft Defender for Endpoint a good alternative to SentinelOne Singularity Endpoint? Often, yes. Microsoft Defender for Endpoint and SentinelOne Singularity Endpoint are both Endpoint Detection and Response products, and both cover Ransomware Prevention. Use the table above to see where features, deployment and company size fit differ. ## Related comparisons - [Microsoft Defender for Endpoint vs Huawei HiSec Endpoint](https://cybersectools.com/compare/huawei-hisec-endpoint-vs-microsoft-defender-for-endpoint) - [Microsoft Defender for Endpoint vs Viettel VCS-aJiant](https://cybersectools.com/compare/microsoft-defender-for-endpoint-vs-viettel-vcs-ajiant) - [Microsoft Defender for Endpoint vs Somansa Privacy-i EDR](https://cybersectools.com/compare/microsoft-defender-for-endpoint-vs-somansa-privacy-i-edr) - [SentinelOne Singularity Endpoint vs Huawei HiSec Endpoint](https://cybersectools.com/compare/huawei-hisec-endpoint-vs-sentinelone-singularity-endpoint) - [SentinelOne Singularity Endpoint vs Viettel VCS-aJiant](https://cybersectools.com/compare/sentinelone-singularity-endpoint-vs-viettel-vcs-ajiant) - [SentinelOne Singularity Endpoint vs Somansa Privacy-i EDR](https://cybersectools.com/compare/sentinelone-singularity-endpoint-vs-somansa-privacy-i-edr) ## Alternatives to each - [See all Microsoft Defender for Endpoint alternatives](https://cybersectools.com/alternatives/microsoft-defender-for-endpoint) - [See all SentinelOne Singularity Endpoint alternatives](https://cybersectools.com/alternatives/sentinelone-singularity-endpoint) --- Source: https://cybersectools.com/compare/microsoft-defender-for-endpoint-vs-sentinelone-singularity-endpoint For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/microsoft-defender-for-endpoint.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md. More on Microsoft Defender for Endpoint and SentinelOne Singularity Endpoint: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md