# Kaseya 365 Endpoint vs ThreatDown Application Block: side-by-side comparison (2026)

[Kaseya 365 Endpoint](https://cybersectools.com/tools/kaseya-kaseya-365-endpoint) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [Kaseya](https://cybersectools.com/companies/kaseya). [ThreatDown Application Block](https://cybersectools.com/tools/threatdown-application-block) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ThreatDown by Malwarebytes](https://cybersectools.com/companies/threatdown-by-malwarebytes). Features, integrations, deployment and the company behind each one, side by side.

## Side-by-side comparison

| | Kaseya 365 Endpoint | ThreatDown Application Block |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Endpoint Protection Platform | Endpoint Protection Platform |
| Verified | No | No |
| Deployment type | Cloud | Cloud |
| Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise |
| Company | Kaseya | ThreatDown by Malwarebytes |
| Headquarters | – | – |

### Use cases and capabilities

| | Kaseya 365 Endpoint | ThreatDown Application Block |
|---|---|---|
| Patch Management | Yes | – |
| Ransomware Prevention | Yes | – |

### Core features

**Kaseya 365 Endpoint**

10 features listed. Sign in on the page to see them.

**ThreatDown Application Block**

5 features listed. Sign in on the page to see them.

## Kaseya 365 Endpoint vs ThreatDown Application Block FAQ

Common questions when comparing Kaseya 365 Endpoint vs ThreatDown Application Block for endpoint protection platform.

### What is the difference between Kaseya 365 Endpoint and ThreatDown Application Block?

**Kaseya 365 Endpoint**: Unified endpoint mgmt platform with RMM, EDR, AV, backup & patch mgmt. Built by Kaseya.

**ThreatDown Application Block**: Blocks unwanted applications from launching on endpoints to reduce attack surface. Built by ThreatDown by Malwarebytes.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Kaseya 365 Endpoint and ThreatDown Application Block?

**Kaseya 365 Endpoint** is made by Kaseya. **ThreatDown Application Block** is made by ThreatDown by Malwarebytes. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Kaseya 365 Endpoint a good alternative to ThreatDown Application Block?

Often, yes. Kaseya 365 Endpoint and ThreatDown Application Block are both Endpoint Protection Platform products. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Kaseya 365 Endpoint vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-kaseya-kaseya-365-endpoint)
- [Kaseya 365 Endpoint vs Bitdefender GravityZone Cloud MSP Security](https://cybersectools.com/compare/bitdefender-gravityzone-cloud-msp-security-vs-kaseya-kaseya-365-endpoint)
- [Kaseya 365 Endpoint vs VIPRE Endpoint Security Cloud](https://cybersectools.com/compare/kaseya-kaseya-365-endpoint-vs-vipre-endpoint-security-cloud)
- [ThreatDown Application Block vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-threatdown-application-block)
- [ThreatDown Application Block vs Bitdefender GravityZone Cloud MSP Security](https://cybersectools.com/compare/bitdefender-gravityzone-cloud-msp-security-vs-threatdown-application-block)
- [ThreatDown Application Block vs VIPRE Endpoint Security Cloud](https://cybersectools.com/compare/threatdown-application-block-vs-vipre-endpoint-security-cloud)

## Alternatives to each

- [See all Kaseya 365 Endpoint alternatives](https://cybersectools.com/alternatives/kaseya-kaseya-365-endpoint)
- [See all ThreatDown Application Block alternatives](https://cybersectools.com/alternatives/threatdown-application-block)

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Source: https://cybersectools.com/compare/kaseya-kaseya-365-endpoint-vs-threatdown-application-block

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/kaseya-kaseya-365-endpoint.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on Kaseya 365 Endpoint and ThreatDown Application Block: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md