# Kaseya 365 Endpoint vs OPSWAT MetaDefender Endpoint: side-by-side comparison (2026)

[Kaseya 365 Endpoint](https://cybersectools.com/tools/kaseya-kaseya-365-endpoint) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [Kaseya](https://cybersectools.com/companies/kaseya). [OPSWAT MetaDefender Endpoint](https://cybersectools.com/tools/opswat-metadefender-endpoint) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [OPSWAT](https://cybersectools.com/companies/opswat). Features, integrations, deployment and the company behind each one, side by side.

## Side-by-side comparison

| | Kaseya 365 Endpoint | OPSWAT MetaDefender Endpoint |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Endpoint Protection Platform | Endpoint Protection Platform |
| Verified | No | No |
| Deployment type | Cloud | On-Premises |
| Company size fit | SMB, Mid-Market, Enterprise | Mid-Market, Enterprise |
| Company | Kaseya | OPSWAT |
| Headquarters | – | – |

### Use cases and capabilities

| | Kaseya 365 Endpoint | OPSWAT MetaDefender Endpoint |
|---|---|---|
| Patch Management | Yes | – |
| Ransomware Prevention | Yes | – |
| Sandbox | – | Yes |
| USB | – | Yes |

### Core features

**Kaseya 365 Endpoint**

10 features listed. Sign in on the page to see them.

**OPSWAT MetaDefender Endpoint**

10 features listed. Sign in on the page to see them.

### Integrations

**Kaseya 365 Endpoint**

No integrations listed.

**OPSWAT MetaDefender Endpoint**

3 integrations listed. Sign in on the page to see them.

## Which one fits you

Based on what each listing shows: deployment, company size, price and open source.

- [Kaseya 365 Endpoint](https://cybersectools.com/tools/kaseya-kaseya-365-endpoint) fits if you want a cloud product and you are a small business.
- [OPSWAT MetaDefender Endpoint](https://cybersectools.com/tools/opswat-metadefender-endpoint) fits if you need to run it on your own servers.

## Kaseya 365 Endpoint vs OPSWAT MetaDefender Endpoint FAQ

Common questions when comparing Kaseya 365 Endpoint vs OPSWAT MetaDefender Endpoint for endpoint protection platform.

### What is the difference between Kaseya 365 Endpoint and OPSWAT MetaDefender Endpoint?

**Kaseya 365 Endpoint**: Unified endpoint mgmt platform with RMM, EDR, AV, backup & patch mgmt. Built by Kaseya.

**OPSWAT MetaDefender Endpoint**: Protects endpoints from peripheral and removable media threats with multiscanning. Built by OPSWAT.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Kaseya 365 Endpoint and OPSWAT MetaDefender Endpoint?

**Kaseya 365 Endpoint** is made by Kaseya. **OPSWAT MetaDefender Endpoint** is made by OPSWAT. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Kaseya 365 Endpoint a good alternative to OPSWAT MetaDefender Endpoint?

Often, yes. Kaseya 365 Endpoint and OPSWAT MetaDefender Endpoint are both Endpoint Protection Platform products. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Kaseya 365 Endpoint vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-kaseya-kaseya-365-endpoint)
- [Kaseya 365 Endpoint vs Bitdefender GravityZone Cloud MSP Security](https://cybersectools.com/compare/bitdefender-gravityzone-cloud-msp-security-vs-kaseya-kaseya-365-endpoint)
- [Kaseya 365 Endpoint vs Bitdefender GravityZone Security for Workstations](https://cybersectools.com/compare/bitdefender-gravityzone-security-for-workstations-vs-kaseya-kaseya-365-endpoint)
- [OPSWAT MetaDefender Endpoint vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-opswat-metadefender-endpoint)
- [OPSWAT MetaDefender Endpoint vs Bitdefender GravityZone Cloud MSP Security](https://cybersectools.com/compare/bitdefender-gravityzone-cloud-msp-security-vs-opswat-metadefender-endpoint)
- [OPSWAT MetaDefender Endpoint vs Bitdefender GravityZone Security for Workstations](https://cybersectools.com/compare/bitdefender-gravityzone-security-for-workstations-vs-opswat-metadefender-endpoint)

## Alternatives to each

- [See all Kaseya 365 Endpoint alternatives](https://cybersectools.com/alternatives/kaseya-kaseya-365-endpoint)
- [See all OPSWAT MetaDefender Endpoint alternatives](https://cybersectools.com/alternatives/opswat-metadefender-endpoint)

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Source: https://cybersectools.com/compare/kaseya-kaseya-365-endpoint-vs-opswat-metadefender-endpoint

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More on Kaseya 365 Endpoint and OPSWAT MetaDefender Endpoint: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md
