# Infonaligy Proofpoint Email Security vs Microsoft Defender for Office 365: side-by-side comparison (2026) [Infonaligy Proofpoint Email Security](https://cybersectools.com/tools/infonaligy-proofpoint-email-security) is a commercial [email security platforms](https://cybersectools.com/categories/email-security-platforms) solution by [Infonaligy](https://cybersectools.com/companies/infonaligy). [Microsoft Defender for Office 365](https://cybersectools.com/tools/microsoft-defender-for-office-365) is a commercial [email security platforms](https://cybersectools.com/categories/email-security-platforms) solution by [Microsoft](https://cybersectools.com/companies/microsoft). Features, integrations, deployment and the company behind each one, side by side. ## Our take What our shortlists say about the one we picked. ### [Microsoft Defender for Office 365](https://cybersectools.com/tools/microsoft-defender-for-office-365) Best for: Teams running Microsoft 365 It is on the list because it is built into Microsoft 365, and many companies already own it through their license, so the buying question is often settled before you start. That makes it the natural first layer if you run Microsoft 365. Decide whether it covers your risk alone or needs a second product beside it, since it is built to work with other email security products. From [Best Email Security Solutions for Business](https://cybersectools.com/shortlists/best-email-security-platforms), Fall 2026. Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about). Need the answer fast? [Best Email Security Solutions for Business](https://cybersectools.com/shortlists/best-email-security-platforms) picks Proofpoint Core Email Protection, Microsoft Defender for Office 365, Mimecast Advanced Email Security and 4 more. ## Side-by-side comparison | | Infonaligy Proofpoint Email Security | Microsoft Defender for Office 365 | |---|---|---| | Pricing model | Commercial | Commercial | | Category | Email Security Platforms | Email Security Platforms | | Verified | No | No | | Deployment type | Cloud | Cloud | | Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise | | Company | Infonaligy | Microsoft | | Headquarters | – | – | ### Use cases and capabilities | | Infonaligy Proofpoint Email Security | Microsoft Defender for Office 365 | |---|---|---| | DMARC | Yes | – | | DKIM | Yes | – | | SPF | Yes | – | | Microsoft 365 | – | Yes | ### Core features **Infonaligy Proofpoint Email Security** 10 features listed. Sign in on the page to see them. **Microsoft Defender for Office 365** 10 features listed. Sign in on the page to see them. ### Integrations **Infonaligy Proofpoint Email Security** 1 integration listed. Sign in on the page to see them. **Microsoft Defender for Office 365** 4 integrations listed. Sign in on the page to see them. ## Infonaligy Proofpoint Email Security vs Microsoft Defender for Office 365 FAQ Common questions when comparing Infonaligy Proofpoint Email Security vs Microsoft Defender for Office 365 for email security platforms. ### What is the difference between Infonaligy Proofpoint Email Security and Microsoft Defender for Office 365? **Infonaligy Proofpoint Email Security**: Managed Proofpoint email security service for phishing & BEC protection. Built by Infonaligy. **Microsoft Defender for Office 365**: Email and collaboration security for Microsoft 365 environments. Built by Microsoft. The table above shows where their features, integrations, deployment and company size fit differ. ### Who makes Infonaligy Proofpoint Email Security and Microsoft Defender for Office 365? **Infonaligy Proofpoint Email Security** is made by Infonaligy. **Microsoft Defender for Office 365** is made by Microsoft. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit. ### Is Infonaligy Proofpoint Email Security a good alternative to Microsoft Defender for Office 365? Often, yes. Infonaligy Proofpoint Email Security and Microsoft Defender for Office 365 are both Email Security Platforms products. Use the table above to see where features, deployment and company size fit differ. ## Related comparisons - [Infonaligy Proofpoint Email Security vs Red Sift OnDMARC](https://cybersectools.com/compare/infonaligy-proofpoint-email-security-vs-red-sift-ondmarc) - [Infonaligy Proofpoint Email Security vs MX Layer Outbound Email Filtering](https://cybersectools.com/compare/infonaligy-proofpoint-email-security-vs-mx-layer-outbound-email-filtering) - [Infonaligy Proofpoint Email Security vs INKY DMARC Monitoring](https://cybersectools.com/compare/infonaligy-proofpoint-email-security-vs-inky-dmarc-monitoring) - [Microsoft Defender for Office 365 vs Red Sift OnDMARC](https://cybersectools.com/compare/microsoft-defender-for-office-365-vs-red-sift-ondmarc) - [Microsoft Defender for Office 365 vs MX Layer Outbound Email Filtering](https://cybersectools.com/compare/microsoft-defender-for-office-365-vs-mx-layer-outbound-email-filtering) - [Microsoft Defender for Office 365 vs INKY DMARC Monitoring](https://cybersectools.com/compare/inky-dmarc-monitoring-vs-microsoft-defender-for-office-365) ## Alternatives to each - [See all Infonaligy Proofpoint Email Security alternatives](https://cybersectools.com/alternatives/infonaligy-proofpoint-email-security) - [See all Microsoft Defender for Office 365 alternatives](https://cybersectools.com/alternatives/microsoft-defender-for-office-365) --- Source: https://cybersectools.com/compare/infonaligy-proofpoint-email-security-vs-microsoft-defender-for-office-365 For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/infonaligy-proofpoint-email-security.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md. More on Infonaligy Proofpoint Email Security and Microsoft Defender for Office 365: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md