# ESET PROTECT vs ThreatLocker Application Allowlisting: side-by-side comparison (2026) [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ESET](https://cybersectools.com/companies/eset). [ThreatLocker Application Allowlisting](https://cybersectools.com/tools/threatlocker-application-allowlisting) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ThreatLocker](https://cybersectools.com/companies/threatlocker). Features, integrations, deployment and the company behind each one, side by side. ## Our take What our shortlists say about the one we picked. ### [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) Best for: Smaller teams wanting a light agent Its place on the list comes from fit with smaller IT teams, because it plugs into the RMM platforms that IT staff and service providers already use. Its size fit runs from startups to enterprise, and you can keep the console on premises if your policy needs that. Check which add-ons you need, since encryption and multi-factor authentication come separately. From [Best Endpoint Security Solutions for Business](https://cybersectools.com/shortlists/best-endpoint-security-solutions), Fall 2026. Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about). ## Side-by-side comparison | | ESET PROTECT | ThreatLocker Application Allowlisting | |---|---|---| | Pricing model | Commercial | Commercial | | Category | Endpoint Protection Platform | Endpoint Protection Platform | | Verified | No | No | | Deployment type | Hybrid | On-Premises | | Company size fit | Startup, SMB, Mid-Market, Enterprise | Startup, SMB, Mid-Market, Enterprise | | Company | ESET | ThreatLocker | | Headquarters | – | – | ### Use cases and capabilities | | ESET PROTECT | ThreatLocker Application Allowlisting | |---|---|---| | Ransomware Prevention | Yes | Yes | | Whitelist | – | Yes | ### Core features **ESET PROTECT** 10 features listed. Sign in on the page to see them. **ThreatLocker Application Allowlisting** 10 features listed. Sign in on the page to see them. ### Integrations **ESET PROTECT** 17 integrations listed. Sign in on the page to see them. **ThreatLocker Application Allowlisting** No integrations listed. ## Which one fits you Based on what each listing shows: deployment, company size, price and open source. - [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) fits if you need both cloud and on-premises options. - [ThreatLocker Application Allowlisting](https://cybersectools.com/tools/threatlocker-application-allowlisting) fits if you need to run it on your own servers. ## ESET PROTECT vs ThreatLocker Application Allowlisting FAQ Common questions when comparing ESET PROTECT vs ThreatLocker Application Allowlisting for endpoint protection platform. ### What is the difference between ESET PROTECT and ThreatLocker Application Allowlisting? **ESET PROTECT**: Cloud-managed endpoint protection, detection and response for businesses, built by ESET. **ThreatLocker Application Allowlisting**: Application allowlisting that blocks unauthorized software by default, built by ThreatLocker. The table above shows where their features, integrations, deployment and company size fit differ. ### Who makes ESET PROTECT and ThreatLocker Application Allowlisting? **ESET PROTECT** is made by ESET. **ThreatLocker Application Allowlisting** is made by ThreatLocker. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit. ### Is ESET PROTECT a good alternative to ThreatLocker Application Allowlisting? Often, yes. ESET PROTECT and ThreatLocker Application Allowlisting are both Endpoint Protection Platform products, and both cover Ransomware Prevention. Use the table above to see where features, deployment and company size fit differ. ## Related comparisons - [ESET PROTECT vs PC Matic SuperShield](https://cybersectools.com/compare/eset-business-security-vs-pc-matic-supershield) - [ESET PROTECT vs PC Matic](https://cybersectools.com/compare/eset-business-security-vs-pc-matic) - [ESET PROTECT vs Airlock Digital Cyber Resilience](https://cybersectools.com/compare/airlock-digital-cyber-resilience-vs-eset-business-security) - [ThreatLocker Application Allowlisting vs PC Matic SuperShield](https://cybersectools.com/compare/pc-matic-supershield-vs-threatlocker-application-allowlisting) - [ThreatLocker Application Allowlisting vs PC Matic](https://cybersectools.com/compare/threatlocker-application-allowlisting-vs-pc-matic) - [ThreatLocker Application Allowlisting vs Airlock Digital Cyber Resilience](https://cybersectools.com/compare/airlock-digital-cyber-resilience-vs-threatlocker-application-allowlisting) ## Alternatives to each - [See all ESET PROTECT alternatives](https://cybersectools.com/alternatives/eset-business-security) - [See all ThreatLocker Application Allowlisting alternatives](https://cybersectools.com/alternatives/threatlocker-application-allowlisting) --- Source: https://cybersectools.com/compare/eset-business-security-vs-threatlocker-application-allowlisting For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/eset-business-security.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md. More on ESET PROTECT and ThreatLocker Application Allowlisting: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md