# ESET PROTECT vs ThreatDown Application Block: side-by-side comparison (2026) [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ESET](https://cybersectools.com/companies/eset). [ThreatDown Application Block](https://cybersectools.com/tools/threatdown-application-block) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ThreatDown by Malwarebytes](https://cybersectools.com/companies/threatdown-by-malwarebytes). Features, integrations, deployment and the company behind each one, side by side. ## Our take What our shortlists say about the one we picked. ### [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) Best for: Smaller teams wanting a light agent Its place on the list comes from fit with smaller IT teams, because it plugs into the RMM platforms that IT staff and service providers already use. Its size fit runs from startups to enterprise, and you can keep the console on premises if your policy needs that. Check which add-ons you need, since encryption and multi-factor authentication come separately. From [Best Endpoint Security Solutions for Business](https://cybersectools.com/shortlists/best-endpoint-security-solutions), Fall 2026. Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about). ## Side-by-side comparison | | ESET PROTECT | ThreatDown Application Block | |---|---|---| | Pricing model | Commercial | Commercial | | Category | Endpoint Protection Platform | Endpoint Protection Platform | | Verified | No | No | | Deployment type | Hybrid | Cloud | | Company size fit | Startup, SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise | | Company | ESET | ThreatDown by Malwarebytes | | Headquarters | – | – | ### Use cases and capabilities | | ESET PROTECT | ThreatDown Application Block | |---|---|---| | Ransomware Prevention | Yes | – | ### Core features **ESET PROTECT** 10 features listed. Sign in on the page to see them. **ThreatDown Application Block** 5 features listed. Sign in on the page to see them. ### Integrations **ESET PROTECT** 17 integrations listed. Sign in on the page to see them. **ThreatDown Application Block** No integrations listed. ## Which one fits you Based on what each listing shows: deployment, company size, price and open source. - [ESET PROTECT](https://cybersectools.com/tools/eset-business-security) fits if you need both cloud and on-premises options and you are a startup. - [ThreatDown Application Block](https://cybersectools.com/tools/threatdown-application-block) fits if you want a cloud product. ## ESET PROTECT vs ThreatDown Application Block FAQ Common questions when comparing ESET PROTECT vs ThreatDown Application Block for endpoint protection platform. ### What is the difference between ESET PROTECT and ThreatDown Application Block? **ESET PROTECT**: Cloud-managed endpoint protection, detection and response for businesses. Built by ESET. **ThreatDown Application Block**: Blocks unwanted applications from launching on endpoints to reduce attack surface. Built by ThreatDown by Malwarebytes. The table above shows where their features, integrations, deployment and company size fit differ. ### Who makes ESET PROTECT and ThreatDown Application Block? **ESET PROTECT** is made by ESET. **ThreatDown Application Block** is made by ThreatDown by Malwarebytes. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit. ### Is ESET PROTECT a good alternative to ThreatDown Application Block? Often, yes. ESET PROTECT and ThreatDown Application Block are both Endpoint Protection Platform products. Use the table above to see where features, deployment and company size fit differ. ## Related comparisons - [ESET PROTECT vs Comodo Advanced Endpoint Protection](https://cybersectools.com/compare/comodo-advanced-endpoint-protection-vs-eset-business-security) - [ESET PROTECT vs Bitdefender GravityZone Small Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-small-business-security-vs-eset-business-security) - [ESET PROTECT vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-eset-business-security) - [ThreatDown Application Block vs Comodo Advanced Endpoint Protection](https://cybersectools.com/compare/comodo-advanced-endpoint-protection-vs-threatdown-application-block) - [ThreatDown Application Block vs Bitdefender GravityZone Small Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-small-business-security-vs-threatdown-application-block) - [ThreatDown Application Block vs Bitdefender GravityZone Business Security](https://cybersectools.com/compare/bitdefender-gravityzone-business-security-vs-threatdown-application-block) ## Alternatives to each - [See all ESET PROTECT alternatives](https://cybersectools.com/alternatives/eset-business-security) - [See all ThreatDown Application Block alternatives](https://cybersectools.com/alternatives/threatdown-application-block) --- Source: https://cybersectools.com/compare/eset-business-security-vs-threatdown-application-block For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/eset-business-security.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md. More on ESET PROTECT and ThreatDown Application Block: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md