# DataSecure RDR vs ThreatLocker Application Allowlisting: side-by-side comparison (2026)

[DataSecure RDR](https://cybersectools.com/tools/datasecure-rdr) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [Cortex Security S.A](https://cybersectools.com/companies/cortex-security-sa). [ThreatLocker Application Allowlisting](https://cybersectools.com/tools/threatlocker-application-allowlisting) is a commercial [endpoint protection platform](https://cybersectools.com/categories/epp) solution by [ThreatLocker](https://cybersectools.com/companies/threatlocker). Features, integrations, deployment and the company behind each one, side by side.

## Side-by-side comparison

| | DataSecure RDR | ThreatLocker Application Allowlisting |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Endpoint Protection Platform | Endpoint Protection Platform |
| Verified | No | No |
| Deployment type | Cloud | On-Premises |
| Company size fit | SMB, Mid-Market, Enterprise | Startup, SMB, Mid-Market, Enterprise |
| Company | Cortex Security S.A. | ThreatLocker |
| Headquarters | – | – |

### Use cases and capabilities

| | DataSecure RDR | ThreatLocker Application Allowlisting |
|---|---|---|
| Ransomware | Yes | – |
| Ransomware Prevention | Yes | Yes |
| Zero Day | Yes | – |
| Anomaly Detection | Yes | – |
| AI Copilot | Yes | – |
| Attack Detection | Yes | – |
| Windows Security | Yes | – |
| Threat Analysis | Yes | – |
| Whitelist | – | Yes |

### Core features

**DataSecure RDR**

8 features listed. Sign in on the page to see them.

**ThreatLocker Application Allowlisting**

10 features listed. Sign in on the page to see them.

### Integrations

**DataSecure RDR**

2 integrations listed. Sign in on the page to see them.

**ThreatLocker Application Allowlisting**

No integrations listed.

## Which one fits you

Based on what each listing shows: deployment, company size, price and open source.

- [DataSecure RDR](https://cybersectools.com/tools/datasecure-rdr) fits if you want a cloud product.
- [ThreatLocker Application Allowlisting](https://cybersectools.com/tools/threatlocker-application-allowlisting) fits if you need to run it on your own servers and you are a startup.

## DataSecure RDR vs ThreatLocker Application Allowlisting FAQ

Common questions when comparing DataSecure RDR vs ThreatLocker Application Allowlisting for endpoint protection platform.

### What is the difference between DataSecure RDR and ThreatLocker Application Allowlisting?

**DataSecure RDR**: AI-powered ransomware detection & response agent with pre-execution blocking. Built by Cortex Security S.A.

**ThreatLocker Application Allowlisting**: Application allowlisting that blocks unauthorized software by default. Built by ThreatLocker.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes DataSecure RDR and ThreatLocker Application Allowlisting?

**DataSecure RDR** is made by Cortex Security S.A. **ThreatLocker Application Allowlisting** is made by ThreatLocker. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is DataSecure RDR a good alternative to ThreatLocker Application Allowlisting?

Often, yes. DataSecure RDR and ThreatLocker Application Allowlisting are both Endpoint Protection Platform products, and both cover Ransomware Prevention. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [DataSecure RDR vs QuellSecure Active Containment](https://cybersectools.com/compare/datasecure-rdr-vs-quellsecure-active-containment)
- [DataSecure RDR vs OnSystem Logic OnSystem Defender](https://cybersectools.com/compare/datasecure-rdr-vs-onsystem-logic-onsystem-defender)
- [DataSecure RDR vs Ivanti Neurons for App Control](https://cybersectools.com/compare/datasecure-rdr-vs-ivanti-neurons-for-app-control)
- [ThreatLocker Application Allowlisting vs QuellSecure Active Containment](https://cybersectools.com/compare/quellsecure-active-containment-vs-threatlocker-application-allowlisting)
- [ThreatLocker Application Allowlisting vs OnSystem Logic OnSystem Defender](https://cybersectools.com/compare/onsystem-logic-onsystem-defender-vs-threatlocker-application-allowlisting)
- [ThreatLocker Application Allowlisting vs Ivanti Neurons for App Control](https://cybersectools.com/compare/threatlocker-application-allowlisting-vs-ivanti-neurons-for-app-control)

## Alternatives to each

- [See all DataSecure RDR alternatives](https://cybersectools.com/alternatives/datasecure-rdr)
- [See all ThreatLocker Application Allowlisting alternatives](https://cybersectools.com/alternatives/threatlocker-application-allowlisting)

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Source: https://cybersectools.com/compare/datasecure-rdr-vs-threatlocker-application-allowlisting

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/datasecure-rdr.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on DataSecure RDR and ThreatLocker Application Allowlisting: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md
