# Claroty xDome Secure Access vs Palo Alto Networks Prisma Access ZTNA 2.0: side-by-side comparison (2026)

[Claroty xDome Secure Access](https://cybersectools.com/tools/claroty-xdome-secure-access) is a commercial [zero trust network access](https://cybersectools.com/categories/ztna) solution by [Claroty](https://cybersectools.com/companies/claroty). [Palo Alto Networks Prisma Access ZTNA 2.0](https://cybersectools.com/tools/palo-alto-networks-prisma-access-ztna) is a commercial [zero trust network access](https://cybersectools.com/categories/ztna) solution by [Palo Alto Networks](https://cybersectools.com/companies/palo-alto-networks). Features, integrations, deployment and the company behind each one, side by side.

## Our take

What our shortlists say about the one we picked.

### [Palo Alto Networks Prisma Access ZTNA 2.0](https://cybersectools.com/tools/palo-alto-networks-prisma-access-ztna)

Best for: Prisma Access customers wanting app-level private access

It earns its place for control inside the session, because App-ID can allow an app but block an upload, and one DLP policy can cover private and SaaS apps. Support for overlapping subnets helps after a merger. It comes as part of Prisma Access for mid-market and enterprise, so weigh it as a platform decision rather than a stand-alone ZTNA buy.

From [Best ZTNA Solutions for Business](https://cybersectools.com/shortlists/best-ztna-solutions), Fall 2026.

Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about).

Need the answer fast? [Best ZTNA Solutions for Business](https://cybersectools.com/shortlists/best-ztna-solutions) picks Zscaler Private Access (ZPA), Netskope One Private Access, Palo Alto Networks Prisma Access ZTNA 2.0 and 4 more.

## Side-by-side comparison

| | Claroty xDome Secure Access | Palo Alto Networks Prisma Access ZTNA 2.0 |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Zero Trust Network Access | Zero Trust Network Access |
| Verified | No | No |
| Deployment type | Hybrid | Cloud |
| Company size fit | Mid-Market, Enterprise | Mid-Market, Enterprise |
| Company | Claroty | Palo Alto Networks |
| Headquarters | – | – |

### Use cases and capabilities

| | Claroty xDome Secure Access | Palo Alto Networks Prisma Access ZTNA 2.0 |
|---|---|---|
| Remote Access | Yes | Yes |
| Network Protection | Yes | – |
| Least Privilege | – | Yes |
| SASE | – | Yes |
| ZTNA | – | Yes |

### Core features

**Claroty xDome Secure Access**

10 features listed. Sign in on the page to see them.

**Palo Alto Networks Prisma Access ZTNA 2.0**

10 features listed. Sign in on the page to see them.

### Integrations

**Claroty xDome Secure Access**

50 integrations listed. Sign in on the page to see them.

**Palo Alto Networks Prisma Access ZTNA 2.0**

14 integrations listed. Sign in on the page to see them.

## Which one fits you

Based on what each listing shows: deployment, company size, price and open source.

- [Claroty xDome Secure Access](https://cybersectools.com/tools/claroty-xdome-secure-access) fits if you need both cloud and on-premises options.
- [Palo Alto Networks Prisma Access ZTNA 2.0](https://cybersectools.com/tools/palo-alto-networks-prisma-access-ztna) fits if you want a cloud product.

## Claroty xDome Secure Access vs Palo Alto Networks Prisma Access ZTNA 2.0 FAQ

Common questions when comparing Claroty xDome Secure Access vs Palo Alto Networks Prisma Access ZTNA 2.0 for zero trust network access.

### What is the difference between Claroty xDome Secure Access and Palo Alto Networks Prisma Access ZTNA 2.0?

**Claroty xDome Secure Access**: Secure remote access solution for cyber-physical systems (CPS), built by Claroty.

**Palo Alto Networks Prisma Access ZTNA 2.0**: Cloud-delivered ZTNA 2.0 for private apps with app-level least-privilege access, built by Palo Alto Networks.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Claroty xDome Secure Access and Palo Alto Networks Prisma Access ZTNA 2.0?

**Claroty xDome Secure Access** is made by Claroty. **Palo Alto Networks Prisma Access ZTNA 2.0** is made by Palo Alto Networks. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Claroty xDome Secure Access a good alternative to Palo Alto Networks Prisma Access ZTNA 2.0?

Often, yes. Claroty xDome Secure Access and Palo Alto Networks Prisma Access ZTNA 2.0 are both Zero Trust Network Access products, and both cover Remote Access. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Claroty xDome Secure Access vs ThreatLocker Zero Trust Network Access](https://cybersectools.com/compare/claroty-xdome-secure-access-vs-threatlocker-zero-trust-network-access)
- [Claroty xDome Secure Access vs Alkira Zero Trust Network Access](https://cybersectools.com/compare/alkira-ztna-vs-claroty-xdome-secure-access)
- [Claroty xDome Secure Access vs Threatmatic Zero Trust Edge](https://cybersectools.com/compare/claroty-xdome-secure-access-vs-threatmatic-zero-trust-edge)
- [Palo Alto Networks Prisma Access ZTNA 2.0 vs ThreatLocker Zero Trust Network Access](https://cybersectools.com/compare/palo-alto-networks-prisma-access-ztna-vs-threatlocker-zero-trust-network-access)
- [Palo Alto Networks Prisma Access ZTNA 2.0 vs Alkira Zero Trust Network Access](https://cybersectools.com/compare/alkira-ztna-vs-palo-alto-networks-prisma-access-ztna)
- [Palo Alto Networks Prisma Access ZTNA 2.0 vs Threatmatic Zero Trust Edge](https://cybersectools.com/compare/palo-alto-networks-prisma-access-ztna-vs-threatmatic-zero-trust-edge)

## Alternatives to each

- [See all Claroty xDome Secure Access alternatives](https://cybersectools.com/alternatives/claroty-xdome-secure-access)
- [See all Palo Alto Networks Prisma Access ZTNA 2.0 alternatives](https://cybersectools.com/alternatives/palo-alto-networks-prisma-access-ztna)

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Source: https://cybersectools.com/compare/claroty-xdome-secure-access-vs-palo-alto-networks-prisma-access-ztna

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/claroty-xdome-secure-access.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on Claroty xDome Secure Access and Palo Alto Networks Prisma Access ZTNA 2.0: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md
