# Cisco XDR vs ReliaQuest GreyMatter: side-by-side comparison (2026)

[Cisco XDR](https://cybersectools.com/tools/cisco-xdr) is a commercial [extended detection and response](https://cybersectools.com/categories/xdr) solution by [Cisco](https://cybersectools.com/companies/cisco). [ReliaQuest GreyMatter](https://cybersectools.com/tools/reliaquest-greymatter) is a commercial [extended detection and response](https://cybersectools.com/categories/xdr) solution by [ReliaQuest](https://cybersectools.com/companies/reliaquest). Features, integrations, deployment and the company behind each one, side by side.

## Side-by-side comparison

| | Cisco XDR | ReliaQuest GreyMatter |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Extended Detection and Response | Extended Detection and Response |
| Verified | No | No |
| Deployment type | Cloud | Cloud |
| Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise |
| Company | Cisco | ReliaQuest |
| Headquarters | – | – |

### Use cases and capabilities

| | Cisco XDR | ReliaQuest GreyMatter |
|---|---|---|
| MITRE ATT&CK | Yes | – |
| Security Orchestration | – | Yes |

### Core features

**Cisco XDR**

10 features listed. Sign in on the page to see them.

**ReliaQuest GreyMatter**

10 features listed. Sign in on the page to see them.

### Integrations

**Cisco XDR**

8 integrations listed. Sign in on the page to see them.

**ReliaQuest GreyMatter**

34 integrations listed. Sign in on the page to see them.

## Cisco XDR vs ReliaQuest GreyMatter FAQ

Common questions when comparing Cisco XDR vs ReliaQuest GreyMatter for extended detection and response.

### What is the difference between Cisco XDR and ReliaQuest GreyMatter?

**Cisco XDR**: XDR platform with AI-driven threat detection across network, endpoint, email, cloud. Built by Cisco.

**ReliaQuest GreyMatter**: Agentic AI security operations platform for autonomous threat investigation. Built by ReliaQuest.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes Cisco XDR and ReliaQuest GreyMatter?

**Cisco XDR** is made by Cisco. **ReliaQuest GreyMatter** is made by ReliaQuest. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is Cisco XDR a good alternative to ReliaQuest GreyMatter?

Often, yes. Cisco XDR and ReliaQuest GreyMatter are both Extended Detection and Response products. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [Cisco XDR vs ThreatDefence SecOps Platform](https://cybersectools.com/compare/cisco-xdr-vs-threatdefence-secops-platform)
- [Cisco XDR vs Microsoft Defender XDR](https://cybersectools.com/compare/cisco-xdr-vs-microsoft-defender-xdr)
- [Cisco XDR vs Seqrite XDR](https://cybersectools.com/compare/cisco-xdr-vs-seqrite-xdr)
- [ReliaQuest GreyMatter vs ThreatDefence SecOps Platform](https://cybersectools.com/compare/reliaquest-greymatter-vs-threatdefence-secops-platform)
- [ReliaQuest GreyMatter vs Microsoft Defender XDR](https://cybersectools.com/compare/microsoft-defender-xdr-vs-reliaquest-greymatter)
- [ReliaQuest GreyMatter vs Seqrite XDR](https://cybersectools.com/compare/reliaquest-greymatter-vs-seqrite-xdr)

## Alternatives to each

- [See all Cisco XDR alternatives](https://cybersectools.com/alternatives/cisco-xdr)
- [See all ReliaQuest GreyMatter alternatives](https://cybersectools.com/alternatives/reliaquest-greymatter)

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Source: https://cybersectools.com/compare/cisco-xdr-vs-reliaquest-greymatter

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/cisco-xdr.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on Cisco XDR and ReliaQuest GreyMatter: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md