# Cisco Duo Remote Access vs Threatmatic Zero Trust Edge: side-by-side comparison (2026) [Cisco Duo Remote Access](https://cybersectools.com/tools/cisco-duo-remote-access) is a commercial [zero trust network access](https://cybersectools.com/categories/ztna) solution by [Duo Security](https://cybersectools.com/companies/duo-security). [Threatmatic Zero Trust Edge](https://cybersectools.com/tools/threatmatic-zero-trust-edge) is a commercial [zero trust network access](https://cybersectools.com/categories/ztna) solution by [Threatmatic](https://cybersectools.com/companies/threatmatic). Features, integrations, deployment and the company behind each one, side by side. ## Our take What our shortlists say about the one we picked. ### [Cisco Duo Remote Access](https://cybersectools.com/tools/cisco-duo-remote-access) Best for: Teams needing phishing-resistant MFA layered on VPN or ZTNA The integration with Cisco XDR for VPN capacity scaling is relevant only if you are already in the Cisco ecosystem. The database lists no specific third-party integrations, which is a gap to verify during evaluation. Duo fits SMB through enterprise teams that want strong MFA and device trust as the foundation of their access security, whether or not they have completed a full VPN-to-ZTNA migration. It is also a natural fit for organizations that have already deployed Duo for MFA and want to extend it into a broader access control posture. From [Best ZTNA Solutions for Business](https://cybersectools.com/shortlists/best-ztna-solutions), Fall 2026. Reviewed by [Nika (Nikoloz) Kokhreidze](https://cybersectools.com/about). Need the answer fast? [Best ZTNA Solutions for Business](https://cybersectools.com/shortlists/best-ztna-solutions) picks Zscaler Private Access (ZPA), Netskope One Private Access, Palo Alto Networks Prisma Access ZTNA 2.0 and 4 more. ## Side-by-side comparison | | Cisco Duo Remote Access | Threatmatic Zero Trust Edge | |---|---|---| | Pricing model | Commercial | Commercial | | Category | Zero Trust Network Access | Zero Trust Network Access | | Verified | No | No | | Deployment type | Cloud | Hybrid | | Company size fit | SMB, Mid-Market, Enterprise | SMB, Mid-Market, Enterprise | | Company | Duo Security | Threatmatic | | Headquarters | – | – | ### Use cases and capabilities | | Cisco Duo Remote Access | Threatmatic Zero Trust Edge | |---|---|---| | Remote Access | Yes | – | | Hybrid Work | Yes | Yes | | ZTNA | Yes | Yes | | Zero Trust Architecture | – | Yes | | Microsegmentation | – | Yes | | Least Privilege | – | Yes | | Network Segmentation | – | Yes | | SASE | – | Yes | | GenAI Security | – | Yes | | Lateral Movement | – | Yes | | Private Networks | – | Yes | ### Core features **Cisco Duo Remote Access** 10 features listed. Sign in on the page to see them. **Threatmatic Zero Trust Edge** 10 features listed. Sign in on the page to see them. ### Integrations **Cisco Duo Remote Access** No integrations listed. **Threatmatic Zero Trust Edge** 3 integrations listed. Sign in on the page to see them. ## Which one fits you Based on what each listing shows: deployment, company size, price and open source. - [Cisco Duo Remote Access](https://cybersectools.com/tools/cisco-duo-remote-access) fits if you want a cloud product. - [Threatmatic Zero Trust Edge](https://cybersectools.com/tools/threatmatic-zero-trust-edge) fits if you need both cloud and on-premises options. ## Cisco Duo Remote Access vs Threatmatic Zero Trust Edge FAQ Common questions when comparing Cisco Duo Remote Access vs Threatmatic Zero Trust Edge for zero trust network access. ### What is the difference between Cisco Duo Remote Access and Threatmatic Zero Trust Edge? **Cisco Duo Remote Access**: Remote access security solution with phishing-resistant MFA and device trust, built by Duo Security. **Threatmatic Zero Trust Edge**: ZTNA platform with microsegmentation, VPN replacement, and GenAI analytics, built by Threatmatic. The table above shows where their features, integrations, deployment and company size fit differ. ### Who makes Cisco Duo Remote Access and Threatmatic Zero Trust Edge? **Cisco Duo Remote Access** is made by Duo Security. **Threatmatic Zero Trust Edge** is made by Threatmatic. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit. ### Is Cisco Duo Remote Access a good alternative to Threatmatic Zero Trust Edge? Often, yes. Cisco Duo Remote Access and Threatmatic Zero Trust Edge are both Zero Trust Network Access products, and both cover ZTNA, Hybrid Work. Use the table above to see where features, deployment and company size fit differ. ## Related comparisons - [Cisco Duo Remote Access vs Zerac Zero Trust Security Platform](https://cybersectools.com/compare/cisco-duo-remote-access-vs-zerac-zero-trust-security-platform) - [Cisco Duo Remote Access vs ThreatLocker Zero Trust Network Access](https://cybersectools.com/compare/cisco-duo-remote-access-vs-threatlocker-zero-trust-network-access) - [Cisco Duo Remote Access vs Bowtie Zero Trust Network Access](https://cybersectools.com/compare/bowtie-zero-trust-network-access-vs-cisco-duo-remote-access) - [Threatmatic Zero Trust Edge vs Zerac Zero Trust Security Platform](https://cybersectools.com/compare/zerac-zero-trust-security-platform-vs-threatmatic-zero-trust-edge) - [Threatmatic Zero Trust Edge vs ThreatLocker Zero Trust Network Access](https://cybersectools.com/compare/threatlocker-zero-trust-network-access-vs-threatmatic-zero-trust-edge) - [Threatmatic Zero Trust Edge vs Bowtie Zero Trust Network Access](https://cybersectools.com/compare/bowtie-zero-trust-network-access-vs-threatmatic-zero-trust-edge) ## Alternatives to each - [See all Cisco Duo Remote Access alternatives](https://cybersectools.com/alternatives/cisco-duo-remote-access) - [See all Threatmatic Zero Trust Edge alternatives](https://cybersectools.com/alternatives/threatmatic-zero-trust-edge) --- Source: https://cybersectools.com/compare/cisco-duo-remote-access-vs-threatmatic-zero-trust-edge For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/cisco-duo-remote-access.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md. More on Cisco Duo Remote Access and Threatmatic Zero Trust Edge: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md