# BluSapphire OneAgent vs Uptycs Nexus: side-by-side comparison (2026)

[BluSapphire OneAgent](https://cybersectools.com/tools/blusapphire-oneagent) is a commercial [endpoint detection and response](https://cybersectools.com/categories/edr) solution by [BluSapphire Cyber Systems](https://cybersectools.com/companies/blusapphire-cyber-systems). [Uptycs Nexus](https://cybersectools.com/tools/uptycs-nexus) is a commercial [endpoint detection and response](https://cybersectools.com/categories/edr) solution by [Uptycs](https://cybersectools.com/companies/uptycs). Features, integrations, deployment and the company behind each one, side by side.

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## Side-by-side comparison

| | BluSapphire OneAgent | Uptycs Nexus |
|---|---|---|
| Pricing model | Commercial | Commercial |
| Category | Endpoint Detection and Response | Endpoint Detection and Response |
| Verified | No | No |
| Deployment type | Hybrid | Cloud |
| Company size fit | Startup, SMB, Mid-Market, Enterprise | Startup, SMB, Mid-Market, Enterprise |
| Company | BluSapphire Cyber Systems | Uptycs |
| Headquarters | – | – |

### Use cases and capabilities

| | BluSapphire OneAgent | Uptycs Nexus |
|---|---|---|
| Ransomware Prevention | Yes | – |
| Zero Day | Yes | – |
| MITRE ATT&CK | Yes | – |
| Linux | Yes | – |
| Windows | Yes | – |
| Workload Security | Yes | – |
| Anomaly Detection | Yes | – |
| Runtime Security | Yes | – |
| Kubernetes | Yes | – |
| Signature Based Detection | Yes | – |
| osquery | – | Yes |

### Core features

**BluSapphire OneAgent**

8 features listed. Sign in on the page to see them.

**Uptycs Nexus**

10 features listed. Sign in on the page to see them.

### Integrations

**BluSapphire OneAgent**

1 integration listed. Sign in on the page to see them.

**Uptycs Nexus**

6 integrations listed. Sign in on the page to see them.

## Which one fits you

Based on what each listing shows: deployment, company size, price and open source.

- [BluSapphire OneAgent](https://cybersectools.com/tools/blusapphire-oneagent) fits if you need both cloud and on-premises options.
- [Uptycs Nexus](https://cybersectools.com/tools/uptycs-nexus) fits if you want a cloud product.

## BluSapphire OneAgent vs Uptycs Nexus FAQ

Common questions when comparing BluSapphire OneAgent vs Uptycs Nexus for endpoint detection and response.

### What is the difference between BluSapphire OneAgent and Uptycs Nexus?

**BluSapphire OneAgent**: Prevention-first next-gen EDR stopping zero-day & ransomware in <20ms, built by BluSapphire Cyber Systems.

**Uptycs Nexus**: Managed SaaS for osquery fleet management across endpoints, built by Uptycs.

The table above shows where their features, integrations, deployment and company size fit differ.

### Who makes BluSapphire OneAgent and Uptycs Nexus?

**BluSapphire OneAgent** is made by BluSapphire Cyber Systems. **Uptycs Nexus** is made by Uptycs. The vendor behind a product decides its roadmap, support, and longevity, so check each company's profile before you commit.

### Is BluSapphire OneAgent a good alternative to Uptycs Nexus?

Often, yes. BluSapphire OneAgent and Uptycs Nexus are both Endpoint Detection and Response products. Use the table above to see where features, deployment and company size fit differ.

## Related comparisons

- [BluSapphire OneAgent vs Somansa Privacy-i EDR](https://cybersectools.com/compare/blusapphire-oneagent-vs-somansa-privacy-i-edr)
- [BluSapphire OneAgent vs AI EdgeLabs Host Platform Security](https://cybersectools.com/compare/ai-edgelabs-host-platform-security-vs-blusapphire-oneagent)
- [BluSapphire OneAgent vs Viettel VCS-aJiant](https://cybersectools.com/compare/blusapphire-oneagent-vs-viettel-vcs-ajiant)
- [Uptycs Nexus vs Somansa Privacy-i EDR](https://cybersectools.com/compare/somansa-privacy-i-edr-vs-uptycs-nexus)
- [Uptycs Nexus vs AI EdgeLabs Host Platform Security](https://cybersectools.com/compare/ai-edgelabs-host-platform-security-vs-uptycs-nexus)
- [Uptycs Nexus vs Viettel VCS-aJiant](https://cybersectools.com/compare/uptycs-nexus-vs-viettel-vcs-ajiant)

## Alternatives to each

- [See all BluSapphire OneAgent alternatives](https://cybersectools.com/alternatives/blusapphire-oneagent)
- [See all Uptycs Nexus alternatives](https://cybersectools.com/alternatives/uptycs-nexus)

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Source: https://cybersectools.com/compare/blusapphire-oneagent-vs-uptycs-nexus

For AI agents: each product above has its own Markdown page (add .md to its URL, for example https://cybersectools.com/tools/blusapphire-oneagent.md). Every CybersecTools shortlist is listed at https://cybersectools.com/shortlists.md.

More on BluSapphire OneAgent and Uptycs Nexus: funding, momentum, hiring and news, plus the full product and company record, are available through the Mandos MCP Server (paid plans), which connects to AI assistants: https://mandos.io/mcp?utm_source=cybersectools.com&utm_medium=compare-md